发明名称 |
Eef2k as Modifiers of the Pten/Akt Pathway and Methods of Use |
摘要 |
Human EEF2K genes are identified as modulators of the PTEN/AKT pathway and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT comprising screening for agents that modulate the activity of EEF2K are provided.
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申请公布号 |
US2008193438(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
US20060908114 |
申请日期 |
2006.03.10 |
申请人 |
EXELIXIS INC. |
发明人 |
BRACE ARTHUR;BLAKE ROBERT A.;FRIEDMAN LORI S.;BJERKE LYNN MARGARET;WARD KEVIN M.;NIETO-BERGMAN SUSANA |
分类号 |
A61K39/395;A61P35/00;C12N5/00;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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