| 摘要 |
The invention relates to a method for determining the generation of thrombin or factor Xa, said generation of activated coagulation factors in various sample materials, such as whole blood or plasma with different thrombocyte quantities, being triggered by phospholipid micelles with different tissue factor contents (0 to 1000 pM). According to the invention, the generation of thrombin is determined in a coagulation machine, which can simultaneously determine classic conventional coagulation parameters. The device for carrying out the method for the parallel determination of thrombin generation and classic conventional coagulation parameters has a rotating cuvette plate, into which a cuvette ring and cuvette elements are inserted. According to the invention, at least one section of the cuvette ring contains a test station for at least two fluorescent test sets and at least four conventional test sets for coagulation, chromogenic substrates and turbidimetric analysis.
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