Bifunctional Enzyme with Y-Glutamylcysteine Synthetase and Glutathione Synthetase Activity and Uses Thereof

摘要

Disclosed herein are DNA molecules isolated from Streptococcus agalactiae and other bacterial species encoding a bifunctional enzyme with gamma-glutamylcysteine synthetase and glutathione synthetase activities. Also disclosed are bifunctional enzymes with gamma-glutamylcysteine synthetase and glutathione synthetase activities, uses of bifunctional enzymes with gamma-glutamylcysteine synthetase and glutathione synthetase activities, uses of inhibitors of bifunctional enzymes with gamma-glutamylcysteine synthetase and glutathione synthetase activities, and uses of DNA molecules encoding bifunctional enzymes encoding enzymes with gamma-glutamylcysteine synthetase and glutathione synthetase activities.