PROCESS FOR THE PREPARATION OF 3,4-DISUBSTITUTED-THIAZOLIDIN-2-ONES
摘要
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
申请公布号
WO2007109786(A3)
申请公布日期
2008.08.14
申请号
WO2007US64786
申请日期
2007.03.23
申请人
INSPIRE PHARMACEUTICALS, INC.;DECAMP, JONATHAN, B.;WATSON, PAUL, S.;SHE, JIN