发明名称 |
GLUCOCORTICOID-LOWERING COMPOSITION |
摘要 |
This disclosure relates to a composition comprising pregnane derivatives according to Formula (I), or a salt, solvate or hydrate thereof, and to a pharmaceutically acceptable carrier or excipient. The composition may be used to lower glucocorticoid level in a human or animal. It may also be used tor modulate activity of enzymes of glucocorticoid metabolism, to modulate RNA transcription and protein level of hypothalamic, hippocampal and pituitary peptides, or for treatment or prophylaxis of human or animal diseases. |
申请公布号 |
WO2008097442(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
WO2008US01060 |
申请日期 |
2008.01.28 |
申请人 |
RUTGERS, THE STATE UNVERSITY OF NEW JERSEY OFFICEOF CORPORATE LIAISON & TECHNOLGY TRANSFER |
发明人 |
KOMARNYTSKYY, SVYATOSLAV;GOVORKO, DMITRY;O'NEAL, JOSEPH;RASKIN, ILYA |
分类号 |
C07J5/00 |
主分类号 |
C07J5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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