摘要 |
The present invention relates to a compound of the Formula (I) or a pharmaceutically acceptable salt thereof, wherein Ar is a group of Formula (II) and salts thereof. Such pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
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申请人 |
PFIZER PRODUCTS INC.;ARCARI, JOEL, THOMAS;BHATTACHARYA, SAMIT, KUMAR;BROSIUS, ARTHUR, DOUGLAS;LUZZIO, MICHAEL, JOSEPH;NELSON, KENDRA, LOUISE;PAN, GONGHUA;SOUTHERS, JAMES, ALFRED, JR.;WISHKA, DONN, GREGORY;XIAO, JUN |
发明人 |
ARCARI, JOEL, THOMAS;BHATTACHARYA, SAMIT, KUMAR;BROSIUS, ARTHUR, DOUGLAS;LUZZIO, MICHAEL, JOSEPH;NELSON, KENDRA, LOUISE;PAN, GONGHUA;SOUTHERS, JAMES, ALFRED, JR.;WISHKA, DONN, GREGORY;XIAO, JUN |