The device has a housing (9) with an opening, in which a lancet holder (6) with a lancet is movably mounted. The holder is connected with a spring unit and has a bearing unit (5), which overlies on a contact surface (20) in the housing in one position of the holder. Two small hooks (3) block a rotation movement of the bearing unit and the contact surface relative to one another, after a release unit of the bearing unit has transferred to another position by the relative rotation movement of the bearing unit and the contact surface.