<p>The invention provides an encapsulated unit dosage form for picoplatin that is adapted for oral administration of the picoplatin containing a substantially dry powder with about 20 to 55 wt% picoplatin in the physical form of a picoplatin particulate wherein an average picoplatin particle diameter is less than about 10 microns. The picoplatin particles are dispersed within the powder of the formulation which includes a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate and an effective amount of up to about 5 wt% of a lubricant.</p>
申请公布号
WO2008097658(A1)
申请公布日期
2008.08.14
申请号
WO2008US01746
申请日期
2008.02.08
申请人
PONIARD PHARMACEUTICALS, INC.;LEIGH, ALISTAIR J.;PROCYSHYN, CHRISTOPHER A.;PHILLIPS, ANGELICA;BREITZ, HAZEL B.
发明人
LEIGH, ALISTAIR J.;PROCYSHYN, CHRISTOPHER A.;PHILLIPS, ANGELICA;BREITZ, HAZEL B.