发明名称 |
POLYETHYLENE GLYCOL DERIVATIVE |
摘要 |
<p>Disclosed are: a novel polyethylene glycol derivative; a drug carrier comprising the derivative; and a pharmaceutical composition comprising the drug carrier having a pharmacologically active substance included therein. Specifically disclosed are: a polyethylene glycol derivative represented by the general formula (I); a drug carrier comprising the derivative and 2-O-(2-diethylaminoethyl)carbamoyl- 1,3-O-dioleoyl-glycerol; and a pharmaceutical composition comprising the drug carrier and a pharmacologically active substance (preferably double-stranded RNA, double-stranded DNA or an oligonucleic acid). Wherein R represents a saturated or unsaturated aliphatic hydrocarbon group having 10 to 30 carbon atoms or a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms; and n represents an integer of 30 to 150.</p> |
申请公布号 |
WO2008096690(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
WO2008JP51719 |
申请日期 |
2008.02.04 |
申请人 |
NIPPON SHINYAKU CO., LTD.;SONOKE, SATORU;UEDA, TOSHIHIRO |
发明人 |
SONOKE, SATORU;UEDA, TOSHIHIRO |
分类号 |
C08G65/333;A61K9/127;A61K31/7088;A61K31/7105;A61K31/711;A61K31/713;A61K47/16;A61K47/24;A61K47/34;A61K48/00;A61P3/00;A61P25/00;A61P29/00;A61P31/12;A61P35/00 |
主分类号 |
C08G65/333 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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