HFC solution formulations containing an anticholinergic

摘要

This invention relates to stable pharmaceutical solution formulations suitable for aerosol administration containing an anticholinergic of formula 1
wherein X - is a pharmaceutically acceptable anion. More particularly, this invention relates to stable pharmaceutical solution formulations suitable for aerosol administration containing an anticholinergic of formula 1 in an environmentally safe hydrofluorocarbon (HFC) as a propellant, together with an organic compound as a cosolvent wherein either an inorganic acid or an organic acid is added to the aerosol solution formulation.