发明名称 |
HIGH PRODUCTION SYSTEM FOR INFECTIOUS HEPATITIS C VIRUS PARTICLE |
摘要 |
<p>The present invention relates to a method for producing infectious hepatitis C virus (HCV) particles, comprising a step of introducing an expression vector into a cell that allows HCV proliferation, such expression vector comprising: DNA sequences encoding the 5' untranslated region, structural proteins, and, if necessary, non-structural proteins of HCV and DNA sequences encoding non-structural proteins and the 3' untranslated region derived from the HCV JFH1 strain, which are located downstream of a polymerase I promoter; and a DNA fragment containing an RNA polymerase I terminator, which is located further downstream thereof.</p> |
申请公布号 |
EP1956087(A1) |
申请公布日期 |
2008.08.13 |
申请号 |
EP20060810936 |
申请日期 |
2006.09.29 |
申请人 |
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES;TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH;TORAY INDUSTRIES, INC. |
发明人 |
TANABE, JUN-ICHI;SONE, SABURO;WAKITA, TAKAJI;ISHII, KOJI;SUZUKI, RYOSUKE;SUZUKI, TETSURO;MIYAMURA, TATSUO |
分类号 |
C12N15/09;C12N7/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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