发明名称 METHOD OF PRODUCTION OF ANTI-INFECTIVE AGENT
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to anti-infective materials (agents) and methods of production thereof, characterised by biocompatibility with animal or human body liquids and tissues. Invention concerns method of production of anti-infective agent, production of anti-infective agent implying modification of inorganic mineral with silico- and alumooxycompounds, namely, Na-shaped bentonite, inorganic metal salts in polar solvent, followed by bentonite keeping in salt solution, isolation of promodified bentonite from solution and drying at temperature not higher 100°C. Before being modified bentonite is enriched with Na+ ions through processing with 3-10% aqueous solution of chloride sodium with following washing and filtering of produced semiproduct thereafter modified by 10-20% inorganic metal salts solution represented with silver nitrate or copper sulphate. Modified bentonite is kept in specified salt solutions within 12-24 hour. Then promodified bentonite is cleared from sodium salts through washing and filtration. After being dried made agent is milled to particle dispersion 20-150 nm. Thus inorganic mineral are processed with specified solutions in ratio, weight fraction bentonite:solution, as 1: (10-40). ^ EFFECT: production of agent with higher anti-infective efficiency using simple and cheap methods and materials. ^ 7 cl, 6 ex
申请公布号 RU2330673(C1) 申请公布日期 2008.08.10
申请号 RU20060141279 申请日期 2006.11.22
申请人 ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "INSTITUT PRIKLADNOJ NANOTEKHNOLOGII" 发明人 ABRAMJAN ARA ARSHAVIROVICH;BEKLEMYSHEV VJACHESLAV IVANOVICH;MAKHONIN IGOR' IVANOVICH;MAKHONIN PETR IVANOVICH;SOLODOVNIKOV VLADIMIR ALEKSANDROVICH
分类号 A61K33/38;A61K33/34;A61K47/02;A61P31/04 主分类号 A61K33/38
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