发明名称 |
СПОСОБ ПОЛУЧЕНИЯ ДИИЗОПРОПИЛ (ГИДРОКСИМЕТИЛ)-ЦИКЛОПРОПИЛ)ОКСИ) МЕТИЛФОСФОНАТА |
摘要 |
Disclosed is a process for preparing a compound of the following formula (2): including the steps of reacting a compound of the following formula (4): with trityl chloride to prepare trityloxy-acetic acid ethyl ester of the following formula (8): reacting the compound of formula (8) with ethyl magnesium halide to prepare 1-trityloxymethyl-cyclopropanol of the following formula (9): combining the 1-trityloxymethyl-cyclopropanol of formula (9) with diisopropylbromo-methylphosphonate in a solvent in the presence of a base to prepare (1-trityloxymethyl-cyclopropoxymethyl)-phosphonic acid diisopropyl ester of the following formula (10): as a solid form, and converting the trityl group of the compound of formula (10) into a hydroxyl group. |
申请公布号 |
RU2007104036(A) |
申请公布日期 |
2008.08.10 |
申请号 |
RU20070104036 |
申请日期 |
2005.06.27 |
申请人 |
ЭЛ ДЖИ ЛАЙФ САЙЕНСИЗ ЛТД. (KR) |
发明人 |
ЙООН Сук-Киоон (KR);НАМ Кун-Хие (KR);ЛИ Санг-Ху (KR);ДЗОНГ Вон-Кио (KR);ЧОЙ Санг-Чул (KR);ЛИ Ки-Кон (KR) |
分类号 |
C07F9/40;C07C35/04;C07F9/6561 |
主分类号 |
C07F9/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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