发明名称 |
Degraded agonist antibody |
摘要 |
The invention relates to a modified antibody which contains two or more H chain V regions and two or more L chain V regions of monoclonal antibody and can transduce a signal into cells by crosslinking a cell surface molecule(s) to thereby serve as an agonist. The modified antibody can be used as a signal transduction agonist and, therefore, useful as a preventive and/or remedy for various diseases such as cancer, inflammation, hormone disorders and blood diseases. |
申请公布号 |
HK1085932(A1) |
申请公布日期 |
2008.08.08 |
申请号 |
HK20060106076 |
申请日期 |
2006.05.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
NAOSHI FUKUSHIMA;MASAYUKI TSUCHIYA;SHINSUKE UNO;TOSHIHIKO OHTOMO;NAOHIRO YABUTA;HIROYUKI TSUNODA |
分类号 |
A61K;A61K38/00;A61P;C07K;C07K16/24;C07K16/28;C07K16/30 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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