发明名称 |
COMPUESTOS DERIVADOS DE 1-OXA-3-AZAESPIRO[4.5]DECAN-2-ONA; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHO COMPUESTO; Y USO DEL COMPUESTO EN EL TRATAMIENTO DE UN TRASTORNO DE LA ALIMENTACION, OBESIDAD, DEPRESION. |
摘要 |
The present invention relates to novel compounds or a pharmaceutically acceptable salt or solvate thereof, selected from a group consisting of: (trans)-8-({[1-(2-fluorophenyl)-1H-pyrazol-3-yl]amino}methyl)-3-(2-fluoro-3-pyridinyl)-1-oxa-3-azaspiro[4.5]decan-2-one; (trans)-8-({[1-(2-fluorophenyl)-1H-pyrazol-3-yl]amino}methyl)-3-(3-pyridazinyl)-1-oxa-3-azaspiro[4.5]decan-2-one; (trans)-8-({[1-(2-fluorophenyl)-1H-pyrazol-3-yl]amino}methyl)-3-(1-methyl-1H-pyrazol-3-yl)-1-oxa-3-azaspiro[4.5]decan-2-one; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as NPY Y5 receptor antagonists and as agents for the treatment and/or prophylaxis of eating disorders such as a binge eating disorder. |
申请公布号 |
CL2008000304(A1) |
申请公布日期 |
2008.08.08 |
申请号 |
CL20080000304 |
申请日期 |
2008.01.31 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BENTLEY, JONATHAN, BIAGETTI, MATTEO, DI FABIO, ROMANO, GENSKI, THORSTEN, GUERY, SEBASTIEN, KOPF, SILVIA ROSALIA, LESLIE, |
分类号 |
A61K31/501;A61P3/00;A61P25/00;A61P25/24;C07D413/14 |
主分类号 |
A61K31/501 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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