发明名称 NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3)
摘要 A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R 1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R 2 and R 3 represent hydrogen; R 4 , R 5 , R 6 , and R 7 may be the same or different and each represents hydrogen, halogen, C 1-6 alkyl or the like; R 8 represents hydrogen or the like; R 9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen or the like.]
申请公布号 IL188670(D0) 申请公布日期 2008.08.07
申请号 IL20080188670 申请日期 2008.01.08
申请人 TOMOHIRO MATSUSHIMA;HIROSHI OBAISHI;KEIKO TAKAHASHI;SETSUO FUNASAKA;EISAI R& D MANAGEMENT CO., LTD.;SHIROTORI, SHUJI 发明人
分类号 C07D 主分类号 C07D
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