METHOD FOR EVOLUTIONARY DESIGN OF BIOCHEMICAL REACTION NETWORK

摘要

PROBLEM TO BE SOLVED: To provide a method for achieving an optimal function of a biochemical reaction network.

SOLUTION: The reconstruction of a biochemical reaction network of a cell is performed in silico by using an iterative optimization procedures. The method can further include laboratory culturing steps to confirm and possibly expand the determinations made using the in silico method, and to produce a cultured cell, or population of cells, with optimal functions. The current invention includes computer systems and computer products including computer-readable program code for performing the in silico steps of the invention.

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