| 摘要 |
Extended release formulations of S-methyladenosylmethionine (SAMe) are pr ovided, as are methods of treating various disorders using extended release SAMe formulations. The extended release formulations may be used to treat a variety of disorders, including liver disorders, psychiatric disorders and j oint disorders. Thus, extended release SAMe formulations may be used to trea t alcoholic liver disease, fatty liver disease, hepatitis, generalized anxie ty disorder, obsessive compulsive disorder, post traumatic stress disorder, panic disorder, and depressive disorders such as depression (e.g. major clin ical depression) and dysthymia.
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