发明名称 Method of Diagnosing the Risk of Thermolabile Phenotype Diseases by Using Gene
摘要 The invention relates to a method of diagnosing a risk of a thermolabile phenotype disease including or caused by influenza encephalitis/encephalopathy, Reye's syndrome, RS virus infectious disease, adenovirus infectious disease, rhinovirus infectious diseases, bastard measles, Japanese encephalitis, malaria infectious disease, Kawasaki disease and sudden infant death syndrome, characterized by examining whether or not an enzymatic activity of at least one enzyme involved in any of various transporters, carnitine cycle, long-chain beta oxidation cycle, medium-chain/short-chain beta oxidation cycle, electron transfer, synthesis of a ketone and production of ATP involved in energy metabolism in mitochondria is significantly lower compared with healthy subjects at 39° C. or higher when referring the enzymatic activity at 37° C. as to 100%.
申请公布号 US2008187918(A1) 申请公布日期 2008.08.07
申请号 US20050791079 申请日期 2005.11.18
申请人 OTSUKA PHARMACEUTICAL CO., LTD.;THE UNIVERSITY OF TOKUSHIMA 发明人 KIDO HIROSHI;KINOSHITA MORITOSHI;MIZUGUCHI HIROSHI;TAKAHASHI NORIHIKO
分类号 C12Q1/68;C12Q1/00;C12Q1/26;C12Q1/32;C12Q1/34;C12Q1/48 主分类号 C12Q1/68
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