METHODS AND COMPOUNDS FOR TREATMENT, PREVENTION AND DIAGNOSIS OF PARASITIC INFECTION AND DISEASE

摘要

The invention relates to compounds, methods, uses, compositions, kits and packages for the diagnosis, prevention and/or treatment of parasite infection (e.g., Plasmodium parasites) and/or disease (e.g., malaria) based on pantetheinase modulation, as well as based on uses of cystamine, cysteamine, and analogs, derivatives, prodrugs, precursors thereof, and salts thereof. Related methods for diagnosing susceptibility to parasite infection and for identifying or characterizing compounds for the prevention and/or treatment of parasite infection are also described.