METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
摘要
Provided herein are prime-boost regimens and materials used therein. The prime- boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
申请公布号
WO2008094188(A2)
申请公布日期
2008.08.07
申请号
WO2007US16290
申请日期
2007.07.17
申请人
ANZA THERAPEUTICS, INC.;DUBENSKY, THOMAS, W., JR.;BROCKSTEDT, DIRK, G.;LEONG, MEREDITH, L.;BAHJAT, KEITH, S.
发明人
DUBENSKY, THOMAS, W., JR.;BROCKSTEDT, DIRK, G.;LEONG, MEREDITH, L.;BAHJAT, KEITH, S.