METHOD FOR DETECTION OF COMPOUND INTERACTING WITH MOLECULE LOCATED ON CELL MEMBRANE

摘要

Disclosed is a method for detecting a wide variety of compounds each interacting with a target molecule located on a cell membrane in a simple manner and at low cost, which can use a living cell without the need of separating a cell membrane or the like from the cell. Also disclosed is a kit for achieving the method. The method for detecting a compound interacting with a molecule located on a cell membrane comprises the steps of: reacting a cell with a compound having a moiety capable of binding selectively to the molecule located on the cell membrane and a radicalization-promoting moiety; further reacting the cell with a compound having a group capable of being radicalized by the radicalization-promoting moiety and a labeling group; and identifying a compound to which the compound radicalized by the radicalization-promoting moiety is bound.