发明名称 |
Transdermal Preparations and Method for Relieving Side Effects in Pergolide Therapy |
摘要 |
It is intended to provide pergolide-containing transdermal preparations having reduced side effects and exerting sufficient therapeutic effects. Namely, a pergolide-containing transdermal preparation which is capable of achieving a plasma AUC ratio of pergolide or the like to at least one pergolide metabolite of 1:0.5 to 1:5; and/or transdermal preparation containing pergolide and/or a pharmaceutically acceptable salt thereof which is capable of achieving a ratio (A/B) of the maximum plasma level (A) of pergolide and/or a pharmaceutically acceptable salt thereof to the plasma level (B) thereof in the next administration of less than 2.
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申请公布号 |
US2008188509(A1) |
申请公布日期 |
2008.08.07 |
申请号 |
US20080059106 |
申请日期 |
2008.03.31 |
申请人 |
TOSHIMITSU ARATA;AIDA KAZUNOSUKE;TERAHARA TAKAAKI;HIGO NARUHITO |
发明人 |
TOSHIMITSU ARATA;AIDA KAZUNOSUKE;TERAHARA TAKAAKI;HIGO NARUHITO |
分类号 |
A61K31/48;A61K9/70;A61K47/32;A61P25/16 |
主分类号 |
A61K31/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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