发明名称 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS
摘要 <p>There is provided 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide for various uses, as well as pharmaceutical compositions and devices comprising 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide. There is also provided a method for reducing reducible compounds (such as reduction-activated prodrugs, e.g. tretazicar) by contacting those compounds with ±-hydroxycarbonyl compounds capable of forming cyclic dimers.</p>
申请公布号 EP1951213(A1) 申请公布日期 2008.08.06
申请号 EP20060831498 申请日期 2006.12.29
申请人 MORVUS TECHNOLOGY LTD. 发明人 KNOX, RICHARD, JOHN
分类号 C07B31/00;A61K31/045;A61K31/12;A61K31/396;A61K45/06 主分类号 C07B31/00
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