发明名称 |
VANCOMYCIN FORMULATIONS HAVING REDUCED AMOUNT OF HISTAMINE |
摘要 |
<p>A time-released formulation of vancomycin. The invention also includes a vancomycin composition having a reduced level of histamine and a process for reducing the level of histamine in a vancomycin composition. The invention also includes a pharmaceutical composition containing vancomycin that reduces the incidence of Red Man Syndrome, phlebitis, and hypotension. The invention further includes a histamine-free growth media that supports growth of Amycolatopsis orientalis and the fermentation of vancomycin.</p> |
申请公布号 |
EP1951889(A2) |
申请公布日期 |
2008.08.06 |
申请号 |
EP20060827095 |
申请日期 |
2006.10.31 |
申请人 |
HOSPIRA, INC. |
发明人 |
MAY, THOMAS, B.;BLESSING, RICHARD;MENON, SUKUMARAN, K.;OSTROW, DAVID, H. |
分类号 |
A61K35/74;A61K38/14;A61P31/04;C12P21/04 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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