| 摘要 |
The present invention provides apparatus 1 for ionizing an analyte sample with a mass calibrant 5. The apparatus 1 includes an ionization means 15 within an ionization chamber 10, a first passageway 12 for delivering the analyte sample to the ionization chamber, a second passageway 20 leading to a mass analyzer, and a third passageway 30 coupled to the ionization chamber for delivering a mass calibrant 5. Primary ions of either the analyte sample or mass calibrant are generated within the ionization chamber, and gaseous neutral molecules of either the mass calibrant or analyte sample respectively are ionized through interaction with said primary ions. In addition, the present invention also provides calibrant formulations that release mass calibrants in a slow, controlled manner. |
