发明名称 LATENT REACTIVE BLOOD COMPATIBLE AGENTS
摘要 A reagent and related method for use in passivating a biomaterial surface, t he reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a spacer group linking the latent reactive group to the aliphatic acid in a manner that preserves the desired function of each group. Once bound to the surface, via the latent reactive group, the reagent presents the aliphatic acid to the physiological environment, in vivo, in a manner (e.g., concentration and orientation) sufficient to hold and orient albumin.
申请公布号 CA2323627(C) 申请公布日期 2008.08.05
申请号 CA19992323627 申请日期 1999.03.11
申请人 SURMODICS, INC. 发明人 AMOS, RICHARD A.;GUIRE, PATRICK E.;ANDERSON, ARON B.;EVERSON, TERRENCE P.
分类号 A61L27/00;A61L33/18;A61K47/48;A61L27/34;A61L31/00;A61L31/04;A61L31/10;A61L33/00 主分类号 A61L27/00
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