发明名称 IFN-beta liquid formulations
摘要 Interferon-beta liquid formulations stabilized with a polyol, a non-reducing sugar or a amino acid. In particular, the formulations are stabilized with a polyol, such as mannitol. The formulations, preferably, furthermore comprise a buffer, such as acetate buffer, at a pH comprised between 3.0 and 4.0 and human albumin at a minimum quantity. The interferon-beta is preferably recombinant.
申请公布号 US7407651(B2) 申请公布日期 2008.08.05
申请号 US20040892181 申请日期 2004.07.16
申请人 APPLIED RESEARCH SYSTEMS ARS HOLDING NV 发明人 SAMARITANI FABRIZIO;NATALE PATRIZIA
分类号 A61K9/08;A61K45/00;A61K38/00;A61K38/21;A61K47/10;A61K47/12;A61K47/16;A61K47/26;A61K47/42;A61P31/12;A61P35/00;A61P37/00;B65D47/02;B65D49/00;C07K1/00;C07K14/00;C07K17/00 主分类号 A61K9/08
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