发明名称 |
Methods, kits and pharmaceutical compositions for diagnosing, delaying onset of, preventing and/or treating osteoporosis |
摘要 |
The present invention uncovers a highly significant association of SNPs in the CNR2 locus, encoding the cannabinoid receptor 2 protein, with osteoporosis. Methods and kits for determining predisposition to osteoporosis, improving diagnosis in individuals suspected of having osteoporosis are provided. Also provided a method of identifying a putative osteoporosis-causing genetic mutation in a subject.
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申请公布号 |
US7407753(B2) |
申请公布日期 |
2008.08.05 |
申请号 |
US20040851667 |
申请日期 |
2004.05.24 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITYOFJERUSALEM;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
ZIMMER ANDREAS;KARSAK MELIHA;DE VERNEJOUL MARIE-CHRISTINE;BAB ITAI;SHOHAMI ESTHER;MECHOULAM RAPHAEL |
分类号 |
C12Q1/68;C07H21/04;C07K16/18 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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