发明名称 |
FORMA CRISTALINA DEL COMPUESTO 3-{[5-(ACETIDIN-1-ILCARBONIL)PIRACIN-2-IL]OXI}-5-[(1-METILETIL)OXI]-N-1H-PIRAZOL-3-ILBENZAMIDA; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHA FORMA; Y USO PARA EL TRATAMIENTO DE LA DIABETE |
摘要 |
A novel crystalline form of 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide is described in the specification. This compound is a glucokinase (GLK or GK) activator and useful as a pharmaceutical agent in the treatment or prevention of a disease or medical condition mediated through GLK, leading to a decreased glucose threshold for insulin secretion. Processes for the manufacture of the crystalline form, pharmaceutical compositions comprising the crystalline form and the use of the crystalline form in medical treatment are also described. |
申请公布号 |
CL2007003805(A1) |
申请公布日期 |
2008.08.01 |
申请号 |
CL20070003805 |
申请日期 |
2007.12.21 |
申请人 |
ASTRAZENECA AB |
发明人 |
MCCABE, JAMES, TOMKINSON, GARY PETER. |
分类号 |
A61K31/497;A61P3/10;C07D403/12 |
主分类号 |
A61K31/497 |
代理机构 |
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