发明名称 |
NON-INVASIVE OPTICAL ANALYSIS USING SURFACE ENHANCED RAMAN SPECTROSCOPY |
摘要 |
In one aspect, a system for use in product packaging is disclosed that includes a polymeric sensing substrate coupled to a package such that a front sensing surface thereof is in contact with a portion of a product, e.g., a fungible product, stored in the package and a back surface thereof is accessible via an environment external to the package. The system further includes a radiation source adapted to direct radiation to the substrate's back surface such that the radiation would interact with one or more molecular species of the product that are in contact with the substrate's sensing surface. The system also includes a detector that is adapted to detect radiation returning from the substrate in response to its illumination by the radiation source. The front surface of the sensing substrate can comprise a plurality of micron-sized or submicron-sized ridges having a discontinuous or continuous metal coating, e.g., a metallic layer with a thickness in a range of about 10 nm to about 1000 nm (and preferably in a range of about 50 nm to about 120 nm), disposed thereon. |
申请公布号 |
WO2008091858(A2) |
申请公布日期 |
2008.07.31 |
申请号 |
WO2008US51643 |
申请日期 |
2008.01.22 |
申请人 |
PRESIDENT & FELLOWS OF HARVARD COLLEGE;MAZUR, ERIC;DIEBOLD, ERIC |
发明人 |
MAZUR, ERIC;DIEBOLD, ERIC |
分类号 |
G01N21/65;B65D79/02;G09F3/02 |
主分类号 |
G01N21/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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