发明名称 |
TOPICAL MECAMYLAMINE FORMULATIONS FOR OCULAR ADMINISTRATION AND USES THEREOF |
摘要 |
Provided are methods, pharmaceutical formulations and kits thereof for the treatment and/or prevention of conditions mediated by neovascularization, abnormal angiogenesis, vascular permeability, or combinations thereof, of posterior and/or anterior tissues and fluids of the eye, including conditions associated with proliferative retinopathies, for example, diabetic retinopathy, age-related maculopathy, retinopathy of prematurity, retinopathy associated with macular edema, or retinopathy associated with sickle cell disease, using the topical administration of mecamylamine or a pharmaceutically acceptable salt thereof to the eye. Methods of preparing the pharmaceutical formulations are also provided.
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申请公布号 |
WO2007075720(A8) |
申请公布日期 |
2008.07.31 |
申请号 |
WO2006US48487 |
申请日期 |
2006.12.18 |
申请人 |
COMENTIS, INC.;ZHANG, XIAOMING;KENGATHARAN, MURALITHARAN;COOKE, JOHN, P.;TAKRURI, HARUN |
发明人 |
ZHANG, XIAOMING;KENGATHARAN, MURALITHARAN;COOKE, JOHN, P.;TAKRURI, HARUN |
分类号 |
A61K9/00;A61K31/13;A61K47/36 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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