| 发明名称 |
Human antibodies to human delta like ligand 4 |
| 摘要 |
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti-hDII4 antibody or antibody fragment binds hDII4 with an affinity of <=500 pM, as measured by surface plasmon resonance.
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| 申请公布号 |
US2008181899(A1) |
申请公布日期 |
2008.07.31 |
| 申请号 |
US20070002245 |
申请日期 |
2007.12.14 |
| 申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
PAPADOPOULOS NICHOLAS J.;MARTIN JOEL H.;SMITH ERIC;NOGUERA-TROISE IRENE;THURSTON GAVIN |
| 分类号 |
A61K39/395;C07K16/00;C12N5/00;C12N15/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
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