TISSUE CLOSURE, DELIVERY DEVICE AND METHOD OF USE

摘要

A tissue closure assembly and a closure delivery device are provided for closing incisions in a target tissue, such as an artery, vein, fascia or hollow organ. The closure delivery device has a closure deployment mechanism within an elongated cylindrical body with an expanding dilator tip and a control handle with an actuation mechanism for sequentially actuating the expanding dilator tip and the closure deployment mechanism. A lumen locator and anchor mechanism has a guidewire and back bleed lumen, an expandable anchor and, optionally, an arteriotomy cutting blade. Various embodiments of tissue closure assemblies are provided having a first and second tissue closure component for attaching to the target tissue on either side of an intended arteriotomy site and means for approximating the first and second tissue closure component and locking them together to seal the arteriotomy after performing a transluminal procedure through the arteriotomy.