| 摘要 |
The present invention provides aminoside tetracyclic anthraquinones repre sented by formula I or II, wherein the piptides are introduced to connect te tracyclic anthraquinones and fatty acid saturated or unsaturated in order to make the anticancer agents to be absorbed and released selectively; meanwhi le some water-solubility groups are also introduced into the branched chain, aminosaccharide and tetracyclic moiety of the compounds to improve the wate r-solubility. The present invention also provides the preparative method and the use thereof as pharmaceutically active components for treating the dise ases cured by aminoside tetracyclic anthraquinone, for example cancer, such as intestines, liver, gastric, breast, lung, ovary, prostate, brain glioma, lymph, skin, pigment, thyroid gland, multiple bone marrow cancer and leukemi a.
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