摘要 |
The invention provides novel pyrimidine and pyridine derivatives of formula (I) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 ZAP-70), insulin-like growth factor (IGF- 1R), or a combination thereof. |
申请人 |
IRM LLC;MICHELLYS, PIERRE-YVES;PEI, WEI;MARSILJE, THOMAS H.;LU, WENSHUO;CHEN, BEI;UNO, TETSUO;JIN, YUNHO;JIANG, TAO |
发明人 |
MICHELLYS, PIERRE-YVES;PEI, WEI;MARSILJE, THOMAS H.;LU, WENSHUO;CHEN, BEI;UNO, TETSUO;JIN, YUNHO;JIANG, TAO |