| 发明名称 |
Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions |
| 摘要 |
The present invention relates to compounds of formula (I): wherein R is hydrogen or alpha-hydroxy, the hydroxyl group in position 7 is in the alpha or beta position; and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. |
| 申请公布号 |
US2008182832(A1) |
申请公布日期 |
2008.07.31 |
| 申请号 |
US20070819517 |
申请日期 |
2007.06.27 |
| 申请人 |
INTERCEPT PHARMACEUTICALS, INC. |
发明人 |
PELLICCIARI ROBERTO;FIORUCCI STEFANO;PRUZANSKI MARK |
| 分类号 |
A61K31/57;A61P1/00;A61P1/16;A61P3/00;A61P3/10;A61P9/10;C07J9/00 |
主分类号 |
A61K31/57 |
| 代理机构 |
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代理人 |
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| 主权项 |
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