发明名称 |
METHOD FOR EVALUATING THE RESPONSE OF AN INDIVIDUAL TO A TREATMENT WITH A TYPE I INTERFERON (IFN) |
摘要 |
The present invention relates to a method for evaluating the in vivoprese nce of a factor that prevents the biological effect of a type I (IFN) in an individual that is under treatment with said type I interferon. In particula r, the present invention relates to a method for evaluating the in vivo pres ence of antibodies directed against a type I interferon (IFN) in an individu al that is under treatment with said type I interferon. The method comprises incubating a blood sample of said individual in vitrowith a suitable amount of said type I interferon for a suitable period of time, and determining mR NA levels of a biological marker of IFN activity, preferably MxA, in said bl ood sample. The treatment mayinvolve a treatment of multiple sclerosis, HCV or HBV using a type I interferon.
|
申请公布号 |
CA2674880(A1) |
申请公布日期 |
2008.07.31 |
申请号 |
CA20082674880 |
申请日期 |
2008.01.24 |
申请人 |
UNIVERSITE LIBRE DE BRUXELLES |
发明人 |
VOKAER, MATHIEU;OCMANT, ANNICK;GOLDMAN, MICHEL;STORDEUR, PATRICK |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|