发明名称 |
MODULATORS OF THE METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 5 AND USES THEREOF |
摘要 |
Disclosed are compounds and pharmaceutically acceptable salts, which are modulators of the metabotropic glutamate receptor 5, for use in treating drug abuse and other mental disorders, for example, a compound of Formula (I), wherein X, Y, and R<SUP>1</SUP>-R<SUP>4</SUP> are as described or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions and methods of use thereof, which involves administering a therapeutically effective amount of a compound or pharmaceutically acceptable salt to a patient. |
申请公布号 |
WO2008092072(A2) |
申请公布日期 |
2008.07.31 |
申请号 |
WO2008US52032 |
申请日期 |
2008.01.25 |
申请人 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;NEWMAN, AMY HAUCK;KULKARNI, SANTOSH SHRIPAD |
发明人 |
NEWMAN, AMY HAUCK;KULKARNI, SANTOSH SHRIPAD |
分类号 |
C07D213/75;A61K31/44;A61P25/30 |
主分类号 |
C07D213/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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