<p>The present invention provides an apparatus for temporal immersion cell culture comprising: A first container (1 ) for holding culture media; A second container (2) for holding the culturing cells; At least, one tube (3) that connects a port (4) in the first container (1) to a port (5) in the second container (2); and, mechanism to move cyclically the containers (1,2) up and down wherein the culture media on the first container (1 ) migrates by gravity to the second container (2) when the first container (1 ) is in a position higher than the second container (2), and wherein the culture media migrates back by gravity from the second container (2) to the first container (1) when the first container (1) is in a position lower than the second container (2); and wherein the first container (1 ) moves independently from the second container (2).</p>
