发明名称 USE OF CYTOKINES AND MITOGENS TO INHIBIT PATHOLOGICAL IMMUNE RESPONSES
摘要 <P>PROBLEM TO BE SOLVED: To provide a method of treating autoimmune diseases, including both antibody-mediated and cell-mediated disorders. <P>SOLUTION: The methods for inhibiting immune responses in ex vivo peripheral blood mononuclear cells (PBMCs) comprises extracting patient-derived peripheral blood mononuclear cells (PBMCs) from patients, treating the cells with a controlling composition including TGF-&beta; and IL-2 for sufficient time to suppress tissue damage due to immunocytes, and thereafter reintroducing the treated cells into the patients, and thereby autoimmune symptoms are improved. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008174564(A) 申请公布日期 2008.07.31
申请号 JP20080033141 申请日期 2008.02.14
申请人 UNIV OF SOUTHERN CALIFORNIA 发明人 HORWITZ DAVID A
分类号 A61K35/14;A61K35/12;A61P3/10;A61P5/00;A61P7/00;A61P17/00;A61P17/02;A61P19/02;A61P21/04;A61P25/00;A61P37/00;A61P37/02;A61P37/06;C12N5/0783 主分类号 A61K35/14
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