发明名称 METHOD FOR DETERMINING OLIGOSACCHARIDE SEQUENCE WITH HIGH-SPEED AND HIGH-PRECISION BY CONSTRAINT
摘要 PROBLEM TO BE SOLVED: To determine an oligosaccharide sequence from a number of peaks on a mass spectrum at a high speed and a high precision. SOLUTION: Mass analysis is performed including cleavage executing oligosaccharide of an object to be analyzed and a plurality of oligosaccharide fragments acquired by cleavage executing that are cleavage executed, and the acquired plurality of mass data and previously determined various oligosaccharide structures and sequence data are compared to determine the oligosaccharide sequence. Alternatively, huge sequence determining calculations generated by directly determining the oligosaccharide sequence with the combination of mass peaks themselves in the mass spectrum are reduced by the constraints in sequence, structure characteristics in biosynthesis of oligosaccharide and analyzed mass before cleavage. Accordingly, the oligosaccharide sequence indicating by actual spectrum is determined. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008175793(A) 申请公布日期 2008.07.31
申请号 JP20070031252 申请日期 2007.01.16
申请人 REIFYCS INC 发明人 KANAZAWA MITSUHIRO;ANYOJI HISAE
分类号 G01N27/62 主分类号 G01N27/62
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