FACTOR H POLYMORPHISMS IN THE DIAGNOSIS AND THERAPY OF INFLAMMATORY DISEASES SUCH AS AGE-RELATED MACULAR DEGENERATION

摘要

The invention relates to antibodies, including monoclonal and polyclonal, or fragments thereof, which discriminate between the histidine and tyrosine isoforms of Complement Factor H and to their use in diagnostic methods and therapeutic treatments relating to Complement Factor H mediated diseases.