Human monoclonal antibody fab fragments directed against HCV E2 glycoprotein and endowed with in vitro neutralizing activity

摘要

Disclosed is a human antibody, or its functional fragments, directed against the HCV E2 glycoprotein, having a neutralizing activity in vivo; a composition for anti-HCV therapy comprising a therapeutically effective amount of the antibody; a composition for topical use in gel, creme, ointment and ovule formulations; and the use of the antibody for validating anti-HCV vaccines.