发明名称 |
1-aza--bicyclo[3.3.1] nonanes |
摘要 |
The present invention relates to 1-aza-bicycloalkyl derivatives of formula (1)
wherein
A represents O or N(R 1 );
Y represents a group of formula
wherein the left bond is attached to the A group and the right bond is attached to the R group;
R represents a substituted or unsubstituted C 5 -C 10 aryl, substituted or unsubstituted hetero-C 5 -C 10 aryl, a group N(R 1 )(R 4 ), or a group N(R 2 )(CHR 3 R 4 );
R 1 represents hydrogen, C 1 -C 4 alkyl, or CF 3 ;
R 2 represents hydrogen, C 1 -C 4 alkyl, or CF 3 ;
R 3 represents hydrogen, C 1 -C 4 alkyl, or CF 3 ;
R 4 represents a substituted or unsubstituted C 5 -C 10 aryl or a substituted or unsubstituted C 5 -C 10 heteroaryl;
in free base or acid addition salt form. |
申请公布号 |
ZA200609255(B) |
申请公布日期 |
2008.07.30 |
申请号 |
ZA20060009255 |
申请日期 |
2006.11.07 |
申请人 |
NOVARTISAG. |
发明人 |
FEUERBACH, DOMINIC;MILLIER, WERNER;ROY, BERNARD, LUCIEN;TROXLER, THOMAS, J.;HURTH, KONSTANZE;FREDERIKSEN, MATHIAS |
分类号 |
A61K;A61K31/439;A61P;A61P25/00;C07D;C07D471/04;C07D471/08 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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