摘要 |
<p>The present invention relates to metal salophen complexes of general formulas I and/or II
wherein
Me(II)
represents Fe, Co, Ni, Cu, Mn, Zn
Me(III)
represents Fe, Mn, AI, Cr
R 1 to R 8
independently from each other represent hydrogen, halogen, hydroxy, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, trihalomethyl
R 9
represents halogen or acetat
or their salts or esters
for use in prevention and treatment of cancer and to pharmaceutical compositions comprising these metal salophen complexes, especially iron salophen complexes.</p> |