发明名称 Mono-lysine salts of azole compounds
摘要 Mono-lysine salts of triazole compounds having a secondary or tertiary hydroxy group are provided. More particularly, the new water-soluble triazole antifungal mono-lysine salt compounds, or solvates thereof, are provided having the general formula I: wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group. R and R<SUP>1 </SUP>in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole compounds are useful for the treatment of fungal infections and can be administered orally, topically and parenterally.
申请公布号 ZA200709127(B) 申请公布日期 2008.07.30
申请号 ZA20070009127 申请日期 2007.10.23
申请人 ESAI R & D MANAGEMENT CO. LTD. 发明人 GAO, QI;CHEN, CHUNG-PIN, H.;FAKES, MICHAEL, G.;PENDRI, YADAGIRI, R.;KIAU, SUSANNE;VAKKALAGADDA, BLISSE
分类号 A61K;A61P;C07C;C07D 主分类号 A61K
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