发明名称 Pyranone derivatives useful for treating cancer
摘要 The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and R<SUB>1 </SUB>and R<SUB>2 </SUB>is independently a hydrogen atom, an alkyl, cycloalkyl or alkylene, linear or branched group containing 1-20 carbon atoms, optionally substituted by a hydroxyl, amino, ether or halogen group, or R<SUB>1 </SUB>and R<SUB>2 </SUB>form together a cycle of 5, 6, 7 or 8 members which is optionally substituted by a hydroxyl, amino, ether or halogen group including isomers, enantiomers, diastereoisomers and the mixtures thereof. A method for preparing the inventive derivatives and the therapeutic use thereof, in particular for treating cancer, are also disclosed.
申请公布号 US7405309(B2) 申请公布日期 2008.07.29
申请号 US20050585974 申请日期 2005.01.14
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 BAKALA JOANNA;HERLEM DENYSE;BENECHIE EMILE;BIGNON JEROME;KHUONG-HUU FRANCOISE;POTIER, LEGAL REPRESENTATIVE GUY JEAN MARIE;ZELVEYAN, LEGAL REPRESENTATIVE MARIE-CLAUDE DENISE MICHELE;MAGNAN, LEGAL REPRESENTATIVE CATHERINE MARIE GERMAINE;DRION, LEGAL REPRESENTATIVE ODETTE
分类号 C07D309/38;A61K31/366;C07C45/29;C07C45/30;C07C47/273 主分类号 C07D309/38
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