摘要 |
The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and R<SUB>1 </SUB>and R<SUB>2 </SUB>is independently a hydrogen atom, an alkyl, cycloalkyl or alkylene, linear or branched group containing 1-20 carbon atoms, optionally substituted by a hydroxyl, amino, ether or halogen group, or R<SUB>1 </SUB>and R<SUB>2 </SUB>form together a cycle of 5, 6, 7 or 8 members which is optionally substituted by a hydroxyl, amino, ether or halogen group including isomers, enantiomers, diastereoisomers and the mixtures thereof. A method for preparing the inventive derivatives and the therapeutic use thereof, in particular for treating cancer, are also disclosed.
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申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
BAKALA JOANNA;HERLEM DENYSE;BENECHIE EMILE;BIGNON JEROME;KHUONG-HUU FRANCOISE;POTIER, LEGAL REPRESENTATIVE GUY JEAN MARIE;ZELVEYAN, LEGAL REPRESENTATIVE MARIE-CLAUDE DENISE MICHELE;MAGNAN, LEGAL REPRESENTATIVE CATHERINE MARIE GERMAINE;DRION, LEGAL REPRESENTATIVE ODETTE |