| 发明名称 |
Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof |
| 摘要 |
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D<SUB>2 </SUB>and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
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| 申请公布号 |
US7405215(B2) |
申请公布日期 |
2008.07.29 |
| 申请号 |
US20050230917 |
申请日期 |
2005.09.21 |
| 申请人 |
WYETH |
发明人 |
BENNANI YOUSSEF L.;TUMEY LAWRENCE NATHAN;GLEASON ELIZABETH ANN;ROBARGE MICHAEL JOSEPH |
| 分类号 |
C07D417/04;A61K31/501;C07D403/04;C07D413/04 |
主分类号 |
C07D417/04 |
| 代理机构 |
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