发明名称 |
Cathepsin cysteine protease inhibitors |
摘要 |
This invention relates to a class of compounds having the general formula (I) which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
|
申请公布号 |
US7405229(B2) |
申请公布日期 |
2008.07.29 |
申请号 |
US20040560672 |
申请日期 |
2004.06.28 |
申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
BAYLY CHRISTOPHER;BLACK CAMERON;CRANE SHELDON;MCKAY DANIEL J.;OBALLA RENATA;ROBICHAUD JOEL |
分类号 |
A61K31/44;A61K31/417;A61K31/4184;A61K31/445;C07C255/29;C07C311/06;C07C323/25;C07C323/49;C07C323/60;C07C323/61;C07C323/62;C07D211/20;C07D211/80;C07D213/32;C07D213/83;C07D231/12;C07D233/54;C07D233/64;C07D235/04;C07D235/06;C07D257/04 |
主分类号 |
A61K31/44 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|